On June 29, 2023, B&C, along with the Environmental Law Institute and the George Washington University Milken Institute of Public Health, sponsored the all-day virtual conference, TSCA Reform — Seven Years Later. The conference was hugely successful and over 700 people registered for it. The quality of the discussion, the caliber of the participants, and the timeliness of the content motivated us to repurpose the substantive sessions to enable our podcast audience to listen to the sessions in this venue. Our topic in this podcast is the Toxic Substances Control Act’s (TSCA) application to per- and polyfluoroalkyl substances (PFAS) and how the U.S. Environmental Protection Agency’s (EPA) implementation of Lautenberg has influenced EPA’s regulatory actions. Our experts address a range of subjects, including EPA’s evolving definition of PFAS under TSCA, EPA’s TSCA PFAS testing strategy, the PFAS reporting rule under TSCA Section 8(a)(7), and much, much more.