The Office of Foreign Assets Control (OFAC) has adopted a final rule amending the Iranian Transactions and Sanctions Regulations, 31 C.F.R. part 560 (ITSR), to authorise additional transactions relating to medicine, medical devices and agricultural commodities. The rule expands existing general licences in the ITSR that are adopted under the Trade Sanctions Reform and Export Enhancement Act of 2000, as amended (TSRA). It includes new authorisations for training, replacement parts, software and services related to the operation, maintenance and repair of medical devices, and items relating to product defects, recalls and other safety concerns.